Decision Trail
Stage 1: Scope Fit
Feb 7, 2026, 04:53 PMGoRisk: 0%
| Rule | Input | Result | Explanation |
|---|---|---|---|
| modality IN_LIST biologics, gene_therapy, gene therapy, cell_therapy, cell therapy, adc, antibody drug conjugate | small molecule | PASS | modality passed check |
| scale IN_LIST commercial_dp, commercial drug product, commercial scale | not provided | NEEDS_INFO | scale not provided in inquiry |
| modality CONTAINS hpapi category 4 | small molecule | PASS | modality passed check |
| timeline CONTAINS urgent, asap, rush, immediate | not provided | NEEDS_INFO | timeline not provided in inquiry |
| devStage IN_LIST phase 1, phase 2, phase 3, clinical, preclinical | Preclinical | GO | Clinical-stage work is core CDMO capability |
| modality IN_LIST small molecule, peptide, oligonucleotide | small molecule | GO | Modality within standard CDMO capabilities |
Questions still needed:
- What is the scale? (needed for: Commercial drug product volumes exceed facility capacity)
- What is the timeline? (needed for: Aggressive timeline may not be achievable with standard scheduling)
Already answered by narrative:
- modality already answered: "small molecule" (confidence: 0.60)
- modality already answered: "small molecule" (confidence: 0.60)
- devStage already answered: "Preclinical" (confidence: 0.90)
- modality already answered: "small molecule" (confidence: 0.60)
Stage 2: Feasibility
Feb 7, 2026, 04:53 PMConditionalRisk: 27%
| Rule | Input | Result | Explanation |
|---|---|---|---|
| Technical Complexity SCORE > 0.5 | 0.90 | GO | Standard chemistry, within capability |
| Scale Feasibility SCORE > 0.5 | 0.50 | GO | Scale near capacity limits, review needed |
| GMP Implications SCORE > 0.5 | 0.70 | GO | GMP manufacturing required - standard GMP protocols apply |
| Analytical Burden SCORE > 0.5 | 0.80 | GO | Analytical requirements manageable |
| Timeline Realism SCORE > 0.5 | 0.60 | GO | No timeline specified |
| Safety Risks SCORE > 0.5 | 0.90 | GO | No significant safety concerns identified |
Conditions:
- Scale may strain current capacity
Questions still needed:
- What quantity/scale of material is needed?
Manual Overrides (1)
CONDITIONAL→GOSTAGE_2 by ADMIN on Feb 7, 2026, 04:55 PM
Justification: we can do it